Accession Number : AD0638600

Title :   CHOLESTEROL UPTAKE IN THE SERUM OF NORMAL AND HOSPITALIZED INDIVIDUALS.

Corporate Author : SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX

Personal Author(s) : Clark,Dale A. ; Haven,Carrie B. ; Franks,John J.

Report Date : FEB 1962

Pagination or Media Count : 7

Abstract : The capacity of human serum to dissolve cholesterol was measured by a procedure previously developed. Serum was obtained from 34 normal young men and from 14 patients hospitalized for some manifestations of arteriosclerotic cardiovascular disease. All sera dissolved additional cholesterol. Sera from the hospitalized group dissolved at least as much additional cholesterol as did sera from the normal group. This finding suggests that in atherosclerosis the reserve cholesterol transport capacity is not diminished. This statement, however, must be accepted within the limitations of the method and the unknown effects of therapeutic regimens. The amount of additional cholesterol dissolved by a sample of serum is not correlated with the original concentration of cholesterol in the serum. (Author)

Descriptors :   (*CHOLESTEROL, BLOOD SERUM), (*ATHEROSCLEROSIS, CHOLESTEROL), BLOOD CHEMISTRY, CARDIOVASCULAR DISEASES

Subject Categories : Biochemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE