Accession Number : AD0638991

Title :   AN INVESTIGATION OF BIOLOGICAL SYSTEMS BY SLOW NEUTRON INELASTIC SCATTERING.

Descriptive Note : Technical rept.

Corporate Author : FELTMAN RESEARCH LABS PICATINNY ARSENAL DOVER N J

Personal Author(s) : Boutin,H. P.

Report Date : SEP 1966

Pagination or Media Count : 58

Abstract : Several systems of biological interest have been investigated by slow neutron inelastic scattering. The frequencies of molecular vibrations in a 40-800/cm range have been obtained for several polypeptides (polyglutamic acid (PGA), polyglycine, polyleucine). Under certain approximations, the frequency distribution g(mu) of phonons in the sample can be extracted from the scattered neutron intensity. This function g(mu) can in turn be used to calculate some of the thermodynamic parameters such as free energy, enthalpy, or specific heat. This has been applied to the study of the alpha-helix-random coil transition in PGA, and to the denaturation of bovine serum albumun (BSA). Preliminary results on the 'melting' of keratin structure in 7-8 LiBr solution are also presented. (Author)

Descriptors :   (*PEPTIDES, NEUTRON SCATTERING), (*GLUTAMIC ACID, NEUTRON SCATTERING), (*GLYCINE, NEUTRON SCATTERING), NUCLEAR RADIATION SPECTROSCOPY, SERUM ALBUMIN, PHONONS, AMIDES, AMINO ACIDS

Subject Categories : Biochemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE