Accession Number : AD0640826

Title :   DECREASE OF METABOLIC RATE IN CHRONICALLY HYPOTHERMIC CATS WITH PREOPTIC LESIONS,

Corporate Author : NAVAL AIR DEVELOPMENT CENTER JOHNSVILLE PA AEROSPACE MEDICAL RESEARCH DEPT

Personal Author(s) : Jackson,F. H. ; Squires,Russell D.

Report Date : 20 SEP 1966

Pagination or Media Count : 13

Abstract : The oxygen consumption and evaporative water loss rates of unrestrained cats were measured at ambient temperatures of 23 to 24C before and after ablation of the medial preoptic region. Postoperative rates were measured after postoperative weight loss had been regained by the hypothermic cats. The mean change of oxygen consumption per kilogram (-17.3%) was significant at the 2% level. The coefficient of correlation between decrease in metabolic rate and final colonic temperature reached was 0.94 (p<0.02). Evaporative water loss rate was not changed significantly (p<0.4). The decrease in metabolic rate is explained as due to ablation of 'hypothermia detectors' in the median preoptic region which normally drive metabolism to prevent hypothermia at comfortable ambient temperature. (Author)

Descriptors :   (*HYPOTHERMIA, METABOLISM), (*HEAT PRODUCTION(BIOLOGY), BRAIN), (*BODY TEMPERATURE, CONTROL), OXYGEN CONSUMPTION, NERVOUS SYSTEM, SHIVERING, CATS

Subject Categories : Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE