Accession Number : AD0641121

Title :   IN VIVO DEGRADATION OF RADIOACTIVE C14 BUTYL CYANOACRYLATES IN RATS (30 DAYS).

Descriptive Note : Technical rept.,

Corporate Author : WALTER REED ARMY MEDICAL CENTER WASHINGTON D C ARMY MEDICAL BIOMECHANICAL RESEARCH LAB

Personal Author(s) : Pani,K. C. ; Gladieux,Gary ; Lange,Harold

Report Date : AUG 1966

Pagination or Media Count : 10

Abstract : N-Butyl-2-cyanoacrylate is another of the family of cyanoacrylate tissue adhesives. It has proven to be as good an adhesive as methyl-2-cyanoacrylate, but much less histotoxic. It is known that methyl-2-cyano-acrylate is completely degraded in the rat and excreted via the urine, feces, and probably the lungs. This study is designed to investigate the manner and extent to which butyl-2-cyanoacrylate is degraded and excreted from rat implant sites. (Author)

Descriptors :   (*ADHESIVES, METABOLISM), (*SURGICAL IMPLANTATION, DEGRADATION), (*ACRYLIC RESINS, METABOLISM), (*NITRILES, METABOLISM), TRACER STUDIES, IN VIVO ANALYSIS, EXCRETION, RADIOACTIVE ISOTOPES, ESTERS, TISSUES(BIOLOGY)

Subject Categories : Anatomy and Physiology
      Medical Facilities, Equipment and Supplies
      Adhesives, Seals and Binders

Distribution Statement : APPROVED FOR PUBLIC RELEASE