Accession Number : AD0642385

Title :   REGULATION OF RNA SYNTHESIS.

Descriptive Note : Final scientific rept.,

Corporate Author : CENTRE D'ENSEIGNEMENT ET DE RECHERCHES DES INDUSTRIES ALIMENTAIRES ET CHIMIQUES BRUSSELS (BELGIUM)*

Personal Author(s) : Lavalle,R.

Report Date : 30 SEP 1966

Pagination or Media Count : 21

Abstract : Measurements of rRNA and tRNA content of E.Coli Ki2 cells have been made in the following situations: (a) exponential growth in media giving rise to different growth rates; (b) shift up from mineral to rich (in amino acids) medium; (c) starvation of a relaxed mutant; (d) chloramphenicol treatment; (e) shift down from rich to mineral medium. The conclusions are that (1) the stringent control, which acts during an amino acid starvation, works on both rRNA and tRNA; and (2) the control mechanism involved in the regulation of RNA content versus chemical environment works differentially on both species. A mutant with a peculiar behavior during a shift up experiment is described, and a new relaxed mutation is described. (Author)

Descriptors :   (*RIBONUCLEIC ACIDS, BIOSYNTHESIS), GROWTH(PHYSIOLOGY), ESCHERICHIA COLI, MUTATIONS, AMINO ACIDS, CHLORAMPHENICOL, CONTROL, GENETICS

Subject Categories : Biochemistry
      Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE