Accession Number : AD0643511

Title :   DYNAMICS OF RETICULAR AND LIMBIC POST STIMULUS DISCHARGE.

Descriptive Note : Progress rept.,

Corporate Author : EDSEL B FORD INST FOR MEDICAL RESEARCH DETROIT MICH DEPT OF NEUROLOGICAL AND BEHAVIORAL SCIENCES

Personal Author(s) : Proctor,Lorne D.

Report Date : 01 NOV 1966

Pagination or Media Count : 19

Abstract : The reticular and limbic systems post stimulus discharges were observed further, using rats, cats and Nemestrina monkeys. The few microelectrode observations in rats and cats suggested this discharge is not a neural membrane phenomena. In three Nemestrina monkeys repeated stimulation and recording from macroelectrodes revealed the following: (1) The most reliable stimuli were 80% duty cycle 'square wave' impulses with a frequency of 400 cps and voltages ranging from 6 - 15 volts with current flow of approximately 3.0 milliamperes for 10 seconds. The 80% duty cycle and 400 cps were critical parameters. (2) Stimulation in the amygdala produced 3 cps rhythmic discharges interrupted by high amplitude monophasic sharp waves or bursts of high amplitude biphasic waves in the stimulation electrode area and was usually reflected to the cortex. There was a residuum of this discharge even three days post stimulus. (3) Following some such stimulations there were large fluctuating DC shifts in the cortex and/or amygdala areas. (Author)

Descriptors :   (*BRAIN, ELECTROPHYSIOLOGY), NERVE CELLS, ELECTRICAL IMPEDANCE, NERVE IMPULSES, STIMULATION(PHYSIOLOGY), ELECTROENCEPHALOGRAPHY, NEUROLOGY, DEOXYRIBONUCLEIC ACIDS, CATS, MONKEYS, RATS

Subject Categories : Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE