Accession Number : AD0646701

Title :   MOLECULAR NEUROCHEMISTRY OF THE HIPPOCAMPUS AND OTHER BRAIN SITES DURING CONDITIONED AVOIDANCE BEHAVIOR.

Descriptive Note : Research rept.,

Corporate Author : YORK UNIV TORONTO (ONTARIO) MOLECULAR PSYCHOBIOLOGY LAB

Personal Author(s) : Gaito,John ; Davison,James H. ; Mottin,James ; Rigler,Joanne

Report Date : 05 JAN 1967

Pagination or Media Count : 21

Abstract : Two experiments were conducted to evaluate neurochemical changes in the ventral hippocampus of rats in a one way active avoidance conditioning task. The dependent variables were amounts of RNA, DNA, and proteins; ratios of these three; the specific activity of protein and tissue pool fractions; and the relative specific activity of the protein fraction. In these experiments a lower shock level was used than in previous experiments. The learning animals showed a tendency to greater specific activity of TCA and protein fractions and to a greater relative specific activity of the protein fraction in brain tissue than did non-learning animals. The results concerning individual brain tissues suggested that the medial ventral cortex, and possibly the posterior ventral cortex, may be involved in this type of learning. No significant differences were found in the ventral hippocampus. (Author)

Descriptors :   (*BRAIN, NUCLEIC ACIDS), (*CONDITIONED RESPONSE, *NUCLEIC ACIDS), (*LEARNING, NUCLEIC ACIDS), BEHAVIOR, DEOXYRIBONUCLEIC ACIDS, RIBONUCLEIC ACIDS, PROTEINS, TISSUES(BIOLOGY), BIOCHEMISTRY, PSYCHOLOGY

Subject Categories : Psychology
      Biochemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE