Accession Number : AD0646751

Title :   SOME STATISTICAL TREATMENTS COMPATIBLE WITH INDIVIDUAL ORGANISM METHODOLOGY.

Descriptive Note : Progress rept.,

Corporate Author : ARMY MEDICAL RESEARCH LAB FORT KNOX KY

Personal Author(s) : Revusky,Samuel H.

Report Date : 21 FEB 1967

Pagination or Media Count : 49

Abstract : Consider experimental treatments with consequences so irreversible that baseline performance cannot be recovered. The conventional method of assessing the effects of such treatments by statistical means involves separate experimental and control groups. An alternative proposed here is to administer the experimental treatment to each subject, one subject at a time and in a random order; whenever any subject receives the experimental treatment, those subjects which have not yet received it receive a control treatment. This procedure permits results significant at the one-tailed .05 level to be obtained with four subjects; if a two-group procedure evaluated by means of the U test is used, a minimum of six subjects is needed for the same significance level. (Author)

Descriptors :   (*MEDICAL RESEARCH, *STATISTICAL ANALYSIS), POISONING, EXPERIMENTAL DESIGN, THERAPY, IRREVERSIBLE PROCESSES, SAMPLING, LABORATORY ANIMALS

Subject Categories : Animal Husbandry and Veterinary Medicine
      Medicine and Medical Research
      Toxicology
      Statistics and Probability

Distribution Statement : APPROVED FOR PUBLIC RELEASE