Accession Number : AD0647401

Title :   MONOAMINERGIC MECHANISMS IN NERVOUS TISSUE.

Descriptive Note : Final rept. 1 Nov 65-31 Oct 66,

Corporate Author : LUND UNIV (SWEDEN)

Personal Author(s) : Dahl,Erik ; Flack,Bengt

Report Date : 26 JAN 1967

Pagination or Media Count : 15

Abstract : Using the sensitive and specific fluorescence method of FALCK and HILLARP in combination with histochemical methods for cholinesterases, electronmicroscopy and biochemical methods for the localization and estimation of the monaomines, their immediate precursors, and the pertinent enzymes, monoaminergic mechanisms are studies in a broad comparative material. Monoaminergic mechanisms constitute a considerable part in many invertebrate nervous systems and have been studied in detail in numerous species. These studies also led to the finding of a hitherto unknown type of nerve cell i.e. a catecholamine-containing sensory or senso-motoric neuron that has now been localized and mapped out in many species. A comprehensive study on the innervation of the eye and its adnexa has been completed. A characterization of the adrenergic and cholinergic receptors in the hearts of the lamprey and the plaice has been performed. The significance of monoaminergic mechanisms for the development of ventricular fibrillation during induced hypothermia has been extensively studied. A study on adrenergic and cholinergic terminal nervous system has disclosed that such systems may interact probably also by axo-axonatic synapses in several mammalian organs. (Author)

Descriptors :   (*AMINES, *NERVOUS SYSTEM), NERVE CELLS, INVERTEBRATES, ANNELIDA, CRUSTACEA, VERTEBRATES, CHEMORECEPTORS, HEART, HYPOTHERMIA, EYE, GANGLIA, HISTOLOGY, FLUORESCENCE, SWEDEN

Subject Categories : Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE