Accession Number : AD0647796

Title :   CEREBRAL INTEGRATION AND ITS ASSESSMENT BY DRUGS,

Corporate Author : MINNESOTA UNIV MINNEAPOLIS

Personal Author(s) : Marrazzi,Amedeo S. ; Meisch,Richard A. ; Schiele,Burtrum C.

Report Date : 1967

Pagination or Media Count : 4

Abstract : Normal behavior is the homeostatic response of the organism. It operates to preserve life and generally by preserving equilibrium in relation to its environments, internal and external, to achieve satisfaction through the reduction of the signal overload that would otherwise result. Regulatory control ultimately requires central representation of all events and the responses to them - proposed or actual - as input and output signals. Such monitoring, internal display and command signaling goes on in the central nervous system where total homeostasis can be achieved through the integrative interaction of its signals, the neural impulses. The recording of such signals affords a means of identifying some of the elements of integrative interactions, and drugs offer an extremely useful tool for analysis of these interactions. In this way it is shown that exogenous psychotogens, like lysergic acid diethylamide (LSD) tend to disrupt integration as a consequence of the high sensitivity of cerebral association areas to the general synaptic inhibitory action these substances exercise. (Author)

Descriptors :   (*MENTAL DISORDERS, DIAGNOSIS(MEDICINE)), (*LYSERGIC ACIDS, PSYCHIATRY), CENTRAL NERVOUS SYSTEM, PERCEPTION(PSYCHOLOGY), PSYCHOSES, NEUROSES, BEHAVIOR, VISUAL PERCEPTION, PERSONALITY, PERSONALITY TESTS

Subject Categories : Psychology
      Medicine and Medical Research
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE