Accession Number : AD0651239

Title :   CORRELATION OF THE INDICES OF IMMUNOLOGICAL SHIFTS IN ANIMAL ORGANISMS UNDER THE INFLUENCE OF IMMUNIZATION WITH STAPHYLOCOCCUS AND DIPHTHERIA TOXOIDS, REPORT II,

Corporate Author : ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s) : Lizgunova,A. V.

Report Date : JUN 1966

Pagination or Media Count : 8

Abstract : Intracutaneous and subcutaneous immunization with staphylococcus toxoid guaranteed similarly high indices in the intensity of the increase of antibodies (32 AU) and the degree of anti-infection protection (83.3% surviving animals). The results of calculating the dermonecrotic tests with staphylococcus cultures and toxin testified to the greater effectiveness of intracutaneous inoculations in comparison with subcutaneous. The intracutaneous administration of diphtheria toxoid caused an increase in the level of antibodies (an average of up to 15 AU), and an increase of anti-infection protection (57.1% surviving animals), and was accompanied by a sharp suppression of dermonecrotic reactions. The intracutaneous immunization of rabbits with diphtheria and staphylococcus toxoids reflected sharply on the intensity and duration of cutaneous reactions, caused by the administration of the corresponding antigens. (Author)

Descriptors :   (*VACCINES, EFFECTIVENESS), STAPHYLOCOCCUS, CORYNEBACTERIUM DIPHTHERIAE, IMMUNITY, DISEASES, PROTECTION, INJECTIONS(MEDICINE), ANTIGEN ANTIBODY REACTIONS, INTENSITY, RABBITS, USSR

Subject Categories : Medicine and Medical Research
      Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE