Accession Number : AD0653947

Title :   COMPARATIVE STUDY OF ALLERGIC REACTIONS IN MONKEYS TO P.P.D. AND KOCH'S OLD TUBERCULIN.

Descriptive Note : Technical translation,

Corporate Author : SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX

Personal Author(s) : Linnikova,M. A.

Report Date : 1967

Pagination or Media Count : 9

Abstract : P.P.D. possesses obvious advantages over Koch's old tuberculin relative to sensitivity after BCG vaccination. Monkeys show a 50% positive reactivity to P.P.D. and only 16% to Koch's old tuberculin. In lower monkeys, Koch's old tuberculin elicits no allergic reaction, through P.P.D. does. Using this fact, Burnet's hypothesis concerning allergy in lower monkeys was demonstrated to be untenable. Follow-up tuberculin reactivity tests conducted one year later indicated no essential deviation in further allergic reaction development in monkeys. (Author)

Descriptors :   (*TUBERCULIN, *ALLERGIC DISEASES), (*MYCOBACTERIUM TUBERCULOSIS, IMMUNITY), SENSITIVITY, VACCINES, MONKEYS, USSR

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE