Accession Number : AD0654840

Title :   CONTENT OF AMINO-ACIDS IN THE DIFFERENT AREAS OF THE BRAIN UNDER CONDITIONS OF HYPEROXIA,

Corporate Author : DIRECTORATE OF SCIENTIFIC INFORMATION SERVICES OTTAWA (ONTARIO)

Personal Author(s) : Pogorelova,T. N.

Report Date : MAY 1967

Pagination or Media Count : 5

Abstract : The content of free amino-acids was studied in the different areas of the rabbit brain during the pre-paroxysmal and paroxysmal phases of the effect of oxygen under pressure. In rabbits exposed to oxygen at 6 atm pressure the paroxysms began within 12 to 18 minutes. This experiment was terminated upon incidence of an intense paroxysmal attack. The pre-paroxysmal phase was investigated following exposure to oxygen at 3.5 atm. In this case the pre-paroxysmal phase was extended to 100-120 minutes, thus giving one the opportunity to trace the gradual build-up of metabolic disturbances leading to the paroxysms. The amino-acid composition of the different brain areas was investigated by a combined electrophoretic and chromatographic method.

Descriptors :   (*OXYGEN, TOXICITY), (*BRAIN, *AMINO ACIDS), PRESSURE BREATHING, METABOLIC DISEASES, ELECTROPHORESIS, CHROMATOGRAPHIC ANALYSIS, CANADA

Subject Categories : Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE