Accession Number : AD0657632

Title :   VIRAL HEPATITIS: ACUTE AND CONVALESCENT STUDIES.

Descriptive Note : Annual progress rept. 1 Jan-1 Aug 67,

Corporate Author : UNIVERSITY OF WESTERN ONTARIO LONDON DEPT OF CHEMISTRY

Personal Author(s) : Redeker,Allan G.

Report Date : 01 AUG 1967

Pagination or Media Count : 7

Abstract : Studies were made of the acute and convalescent phases of viral hepatitis, both natural (IH) and post-transfusion (SH). These investigations emphasized needle biopsy of the liver, small bowel biopsy and L.E. cell tests. Eighteen cases of fulminant hepatitis with coma were studied. Six patients survived with conservative therapy. Three cases were treated by multiple exchange transfusion, all unsuccessfully. Convalescent (long term follow-up) studies disclosed a number of patients exhibiting a persistent lesion characterized by recurrent transaminase elevations and mild inflammation in the liver upon biopsy. One patient progressed within one year from acute hepatitis to advanced cirrhosis. (Author)

Descriptors :   (*INFECTIOUS HEPATITIS VIRUS, PATHOLOGY), (*HEPATITIS VIRUSES, DISEASES), BIOPSY, LIVER, INTESTINES, THERAPY, BLOOD TRANSFUSION, SERUM HEPATITIS, CONVALESCENCE, BLOOD ANALYSIS, BLOOD CHEMISTRY, ENZYMES

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE