Accession Number : AD0658969

Title :   AVERSION TO SUCROSE PRODUCED BY CONTINGENT X-IRRADIATION: TEMPORAL AND DOSAGE PARAMETERS,

Corporate Author : ARMY MEDICAL RESEARCH LAB FORT KNOX KY

Personal Author(s) : Revusky,Samuel H.

Report Date : 30 JUN 1967

Pagination or Media Count : 16

Abstract : Rats were made familiar with milk in the course of five days. A few days later, experimental Ss were permitted to drink sucrose solution and, from 3.5 to 32 hours afterward, were exposed to 50 roentgens of X-rays. Sham controls were treated in the same way except that they were not X-irradiated. Irradiated controls ate chow instead of drinking sucrose solution prior to irradiation. In a subsequent preference test between sucrose solution and milk, those experimental animals irradiated 6.5 hours or less after sucrose consumption exhibited an aversion to sucrose relative to both type of controls. In a similar later experiment, rats were exposed to 50, 150 or 250 roentgens, 7 hours after they consumed sucrose solution. Subsequent aversion to sucrose solution increased with increasing radiation dose. It is conjectured that similar associations over long time intervals may be involved in the regulation of food intake. (Author)

Descriptors :   (*SUCROSE, INGESTION(PHYSIOLOGY)), (*RADIATION SICKNESS, *INGESTION(PHYSIOLOGY)), RATS, BEHAVIOR, CONSUMPTION, X RAYS, RADIATION EFFECTS

Subject Categories : Radiobiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE