Accession Number : AD0658971

Title :   SUGAR RETENTION, COFACTOR LEVELS, AND LEAKAGE OF METABOLITES IN X-IRRADIATED, STARVED YEAST CELLS.

Descriptive Note : Final rept.,

Corporate Author : ARMY MEDICAL RESEARCH LAB FORT KNOX KY

Personal Author(s) : Doyle,R. J. ; Spoerl,Edward

Report Date : 30 JUN 1967

Pagination or Media Count : 16

Abstract : Irradiated cells retained a greater portion of (14C)sorbose, though rates of efflux were similar during a first phase of exit and rates of uptake were similar. The thiamine pyrophosphate content of irradiated cells was greater than that of unirradiated cells, whereas pyruvate decarboxylase activities and ATP and DPN contents were similar. Similar amounts of 260 millimicrons absorbing materials were lost by irradiated and unirradiated cells during starvation. Incubation with glucose or maltose increased the total loss, while incubation with severa less readily metabolized sugars or with hexitols increased the relative loss from irradiated cells. (Author)

Descriptors :   (*YEASTS, RADIATION EFFECTS), (*CELLS(BIOLOGY), RADIATION EFFECTS), (*METABOLISM, *RADIATION EFFECTS), (*CARBOHYDRATES, METABOLISM), TRACER STUDIES, CULTURE MEDIA, STARVATION, VITAMIN B COMPLEX, SALTS, CARBON DIOXIDE, COENZYMES, ADENOSINE PHOSPHATES, NUCLEOTIDES, X RAYS

Subject Categories : Radiobiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE