Accession Number : AD0658986

Title :   PATHOPHYSIOLOGICAL STUDIES OF TEN POISONOUS SNAKE VENOMS.

Descriptive Note : Rept. for Jan 65-Jun 66,

Corporate Author : EDGEWOOD ARSENAL MD

Personal Author(s) : Vick,James A. ; Ciuchta,Henry P. ; Manthei,James H. ; DeGraff,Richard

Report Date : JUL 1966

Pagination or Media Count : 36

Abstract : In an attempt to determine the exact physiological changes that follow the administration of a lethal dose of snake venom, the following studies were carried out: One thousand eight hundred and sixty-four mice and two hundred and forty-seven dogs were injected with varying doses of venom and changes in EEG, heart rate, EKG, respiration and blood pressure followed until death. Results indicate that on a mg/kg basis, the lethal dose of venom for the dog is significantly less than that for the mouse and that the mechanism of death for most venoms is respiratory in nature. (Author)

Descriptors :   (*VENOMS, PATHOLOGY), REPTILES, PHYSIOLOGY, DOGS, MICE, LETHAL DOSAGE, RESPIRATION, ELECTROENCEPHALOGRAPHY, ELECTROCARDIOGRAPHY, BLOOD PRESSURE

Subject Categories : Anatomy and Physiology
      Medicine and Medical Research
      Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE