Accession Number : AD0661320

Title :   EFFECTS OF MAGNESIUM PEMOLINE UPON HUMAN LEARNING, MEMORY, AND PERFORMANCE TESTS.

Descriptive Note : Technical rept.,

Corporate Author : EDGEWOOD ARSENAL MD

Personal Author(s) : Smith,Ronald G.

Report Date : OCT 1967

Pagination or Media Count : 59

Abstract : The purpose of this report was to determine the effects of magnesium pemoline (a combination of 2-imino-5-phenyl-4-oxazolidinone and magnesium hydroxide) on a variety of human learning, memory, and performance tasks. Magnesium pemoline (25 or 37.5 mg) or a placebo was administered orally on a double-blind basis to intelligence-matched groups of normal, adult males. These agents were administered 3 hr before the testing. Seven different tests were used in the experiment: verbal learning, motor learning, galvanic skin response, classical conditioning, visual short-term memory, auditory short-term memory, visual reaction time, and arm-hand steadiness. From the test results, it was concluded that magnesium pemoline, in the doses tested, does not facilitate learning, memory, or performance in normal, adult men. In fact, the only statistically significant effects indicate that the higher dose was deleterious for verbal and motor learning. (Author)

Descriptors :   (*DRUGS, *PSYCHOLOGICAL TESTS), LEARNING, MEMORY(PSYCHOLOGY), RETENTION(PSYCHOLOGY), PERFORMANCE(HUMAN), RIBONUCLEIC ACIDS, PERFORMANCE(HUMAN), CONDITIONED RESPONSE, GALVANIC SKIN RESPONSE, VERBAL BEHAVIOR, PSYCHOMOTOR TESTS, VISUAL PERCEPTION, AUDITORY PERCEPTION, REFLEXES, REACTION(PSYCHOLOGY), MOTOR REACTIONS, STATISTICAL ANALYSIS

Subject Categories : Psychology
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE