Accession Number : AD0662327

Title :   THE EFFECTS OF DECABORANE ON BLOOD PRESSURE OF RATS.

Descriptive Note : Final rept. May 66-May 67,

Corporate Author : SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX

Personal Author(s) : Foster,Lloyd L. ; Britz,William E. , Jr

Report Date : AUG 1967

Pagination or Media Count : 13

Abstract : Investigations were undertaken to describe the mechanism of cardiovascular toxicity of decaborane-14. Decaborane (20 mg./kg.) injected into rats caused a decrease in systolic pressure, heart rate, and respiration rate. There was no demonstrable change in the diastolic and pulse pressures. The possible mechanisms for these changes are discussed. (Author)

Descriptors :   (*DECABORANES, TOXICITY), BLOOD PRESSURE, CARDIOVASCULAR SYSTEM, DOSAGE, PULSE RATE, RESPIRATION, PHARMACOLOGY

Subject Categories : Anatomy and Physiology
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE