Accession Number : AD0665021

Title :   CARDIAC OUTPUT AND REGIONAL BLOOD FLOW IN CONSCIOUS RATS EXPOSED TO ACUTE HYPOXIA.

Descriptive Note : Joint rept.,

Corporate Author : NAVAL AEROSPACE MEDICAL INST PENSACOLA FLA

Personal Author(s) : Nejad,N. S. ; Fast,Thomas N. ; Ogden,Eric

Report Date : 15 NOV 1967

Pagination or Media Count : 21

Abstract : The effects of hypoxia on cardiac output and fractional distribution of regional blood flow were measured in unrestrained and unanesthetized Sprague-Dawley rats. Cardiac output was determined by thermodilution techniques, while blood distribution was determined by Rb86Cl and iodoantipyrine I131 tracers. The animals were exposed 18-24 hours after cannulation to atmospheres of air and 7 and 10% oxygen in nitrogen. Cardiac output was higher in the hypoxic environments. Fractional distribution to brain, heart, and adrenal was increased, while that to the kidney and spleen was decreased in reduced O2 environments. (Author)

Descriptors :   (*HYPOXIA, *BLOOD CIRCULATION), (*HEART, PERFORMANCE(ENGINEERING)), LABELED SUBSTANCES, BRAIN, ADRENAL GLANDS, RATS, KIDNEYS

Subject Categories : Anatomy and Physiology
      Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE