Accession Number : AD0665791

Title :   HISTOCHEMICAL STUDIES OF SKIN BURNS, CONTACT AND FLASH LAMP BURNS.

Descriptive Note : Progress rept.,

Corporate Author : NAVAL APPLIED SCIENCE LAB BROOKLYN N Y

Personal Author(s) : Mixter,George , Jr. ; Pillsbury,Nan ; Derksen,Willard L.

Report Date : 05 APR 1967

Pagination or Media Count : 26

Abstract : Histochemical studies to evaluate the effects on enzyme activity as a possible cause of cell damage in thermal injury were made on the skin of white rats after contact with a copper block at 60C for 5 seconds and after exposure to thermal radiation of 3.7 calories/sq. cm. from a xenon flash lamp pulse peaking 0.5 milliseconds. The hot copper contact burn caused deep burn lesions with vascular thrombosis. There was no loss of enzyme activity until 4 hours after the burn exposure. The flash lamp exposure showed only shallow tissue damage after 24 hours. There was immediate loss of enzyme activity in the surface epithelium with rapid cell death. (Author)

Descriptors :   (*BURNS(INJURIES), SKIN(ANATOMY)), (*SKIN(ANATOMY), *HISTOLOGICAL TECHNIQUES), XENON LAMPS, THERMAL RADIATION, ENZYMES, TISSUES(BIOLOGY), CELLS(BIOLOGY), DEGRADATION, BLOOD VESSELS, THROMBOSIS

Subject Categories : Medicine and Medical Research
      Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE