Accession Number : AD0667471

Title :   SERUM ENZYME CHANGES AFTER PHYSICAL EXERTION,

Corporate Author : NAVAL MEDICAL FIELD RESEARCH LAB CAMP LEJEUNE N C

Personal Author(s) : Wilson,I. Dodd

Report Date : MAR 1968

Pagination or Media Count : 18

Abstract : A study of alterations in selected serum enzymes after physical exertion by young males is reported. Mean serum concentrations of glutamic oxalacetic transaminase (SGOT), lactate dehydrogenase and amylase all increase after the performance of vigorous exercise. SGOT concentrations in the abnormal range are often reached both immediately after exertion to near exhaustion and on the day following vigorous performance of calisthenics. These evaluations appear to represent two distinct SGOT peaks. Increments in SGOT concentrations found immediately after exercise correlate highly with alterations in blood lactate, blood pyruvate and blood pH, but not with changes in serum potassium. Thus, the initial peak is associated in some unknown manner with anaerobic glycolysis. The second SGOT peak is probably related to the destruction of skeletal muscle. Low resting SGOT concentrations correlate significantly with better performances in physical fitness tests. Also, the later SGOT rise is abolished by a 10-week period of physical conditioning. Thus, the measurement of serum enzyme concentrations appears to be potentially useful in the assessment of physical fitness. (Author)

Descriptors :   (*PHYSICAL FITNESS, BLOOD CHEMISTRY), GLYCOSIDE HYDROLASES, LACTATES, OXIDOREDUCTASES, EXERCISE(PHYSIOLOGY), PH FACTOR, POTASSIUM, PYRUVATES, FATIGUE(PHYSIOLOGY), GLYCOLYSIS

Subject Categories : Personnel Management and Labor Relations
      Biochemistry
      Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE