Accession Number : AD0667566

Title :   FLUOROMETRIC DETECTION OF BIOLOGICAL CHANGES IN IRRADIATED LABORATORY ANIMALS.

Descriptive Note : Formal progress rept. 1 Nov 65-31 Oct 66,

Corporate Author : NORTHROP SPACE LABS HAWTHORNE CALIF

Personal Author(s) : Demetriou,J. A.

Report Date : 31 OCT 1966

Pagination or Media Count : 21

Abstract : The exposure of rats to either 80 or 230 rad of gamma irradiation from a Cobalt-60 source was found to effect the levels of certain fluorescent fractions excreted in urine. In addition to the changes in fluorometrically detectable fractions, an ultraviolet absorbing component, in urine, was found to increase following 80 rad of whole body irradiation. The effects of radiation on body weights, creatinine and urine excretion were observed only at the 230 rad dose. Fluorometric, spectrophotometric, fractionation techniques of urine samples are described. (Author)

Descriptors :   (*RADIATION EFFECTS, FLUORESCENCE), BODY FLUIDS, WHOLE BODY IRRADIATION, URINE, CHROMATOGRAPHIC ANALYSIS, BODY WEIGHT, ULTRAVIOLET SPECTROSCOPY, RADIATION DOSAGE, EXCRETION, RADIOBIOLOGY

Subject Categories : Radiobiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE