Accession Number : AD0667993

Title :   ENDOGENOUS MECHANISM OF VASCULAR RESPONSE IN INFLAMMATION, WITH SPECIAL REFERENCE TO BIOLOGIC SIGNIFICANCE OF SPECIFIC PERMEABILITY FACTORS AND THEIR INHIBITORS NEWLY ISOLATED FROM INFLAMED SITES.

Descriptive Note : Progress rept.,

Corporate Author : KUMAMOTO UNIV (JAPAN) MEDICAL SCHOOL

Personal Author(s) : Hayashi,Hideo

Report Date : DEC 1967

Pagination or Media Count : 8

Abstract : The mechanism of delayed and prolonged vascular permeability changes in inflammation was analysed in the form of chemical mediators. The first purpose was to ascertain the role of permeability factors of peptide nature, which were isolated from the inflamed sites and highly purified, in the permeability changes. The second purpose was to verify the relationship between the chemical structures and biologic actions of the factors. The third purpose was to confirm the biochemical mechanism of the production of the factors in vivo and in vitro. The observations will establish a new and fruitful way for essential understanding of inflammation. (Author)

Descriptors :   (*BLOOD VESSELS, *PERMEABILITY), ANTIGEN ANTIBODY REACTIONS, SKIN(ANATOMY), PEPTIDES, PEPTIDE HYDROLASES, CHROMATOGRAPHIC ANALYSIS, LABELED SUBSTANCES, INJECTIONS(MEDICINE), BURNS(INJURIES), PATHOLOGY, JAPAN

Subject Categories : Biochemistry
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE