Accession Number : AD0669534

Title :   BIOCHEMICAL PROFILE OF NERVE MEMBRANE.

Descriptive Note : Annual rept. no. 3,

Corporate Author : CHILE UNIV SANTIAGO LABORATORIO DE BIOFISICA

Personal Author(s) : Canessa-Fischer,Mitzy ; Vargas,Fernando ; Zamudio,Italo ; Zambrano,Fernando ; Cellino,Marla

Report Date : FEB 1968

Pagination or Media Count : 14

Abstract : A multi-disciplinary approach was used to study the molecular structure and function of nerve membrane in the Chilean squid. Intracellular perfused giant axons were used (1) to study anions and substrate requirements which allow the recovery of the active transport of sodium ions; and (2) to determine the presence of fixed negative charges in the matrix of axon membrane. Intact axons were used to study the transport of rubidium and its relationship with metabolism. Axons isolated from the optic tract of the squid eyes were used to devise a large scale preparation of nerve membranes which will permit the study of its molecular organization. (Author)

Descriptors :   (*NERVE CELLS, CEPHALOPODA), MEMBRANES(BIOLOGY), ELECTROPHYSIOLOGY, OPTIC NERVE, IN VITRO ANALYSIS, TRANSPORT PROPERTIES, ENZYMES, MOLECULAR STRUCTURE, RUBIDIUM, METABOLISM, CHILE

Subject Categories : Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE