Accession Number : AD0670852

Title :   INVESTIGATIONS OF LASER DAMAGE TO OCULAR TISSUES.

Descriptive Note : Final rept. 5 Apr 67-5 Feb 68,

Corporate Author : STANFORD RESEARCH INST MENLO PARK CALIF

Personal Author(s) : Vassiliadis,A. ; Honey,R. C. ; Peppers,N. A. ; Zweng,H. C. ; Rosan,R. C.

Report Date : MAR 1968

Pagination or Media Count : 98

Abstract : Results of experimental investigations to determine threshold levels for minimally-sized retinal lesions caused by neodymium long-pulsed and Q-switched lasers are presented. The experimental animals were rhesus monkeys. In addition, results of retinal damage due to Q-switched ruby, neodymium, and doubled neodymium lasers at suprathreshold energy levels are also presented. A report on histopathology of retinal injury caused by Q-switched lasers is presented. Observations on damage due to both ruby and neodymium lasers are discussed. The design and construction of a fundus reflectometer is described, and preliminary measurements of fundus reflectance of rabbit, rhesus monkey, and human subjects are reported. Results of an experimental investigation to determine threshold damage levels for a CO2 laser to rabbit corneas are given. Data for three exposure times are included. In addition, theoretical calculations based on a one-dimensional heat-flow model are reported, and comparison is made with the experimental results. Finally, some results on permanent corneal damage due to CO2 laser are reported. (Author)

Descriptors :   (*LASERS, *BURNS(INJURIES)), (*EYE, RADIATION INJURIES), THRESHOLDS(PHYSIOLOGY), PATHOLOGY, RETINA, REFLECTOMETERS, RUBY, NEODYMIUM, CARBON DIOXIDE, OPHTHALMOLOGY

Subject Categories : Medicine and Medical Research
      Radiobiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE