Accession Number : AD0671035

Title :   HORMONE METABOLISM IN MEN EXPOSED TO HIGH ELEVATION.

Descriptive Note : Annual rept. no. 2, 1 May 67-30 Apr 68,

Corporate Author : UNIVERSIDAD PERUANA CAYETANO HEREDIA LIMA INSTITUTO DE INVESTIGACIONES DE LA ALTURA

Personal Author(s) : Guerra-Garcia,Roger

Report Date : 30 APR 1968

Pagination or Media Count : 12

Abstract : Data are presented on Testosterone Production Rate (TPR) in eight normal men acutely exposed to high altitude. The mean control value at sea level was 6.693 mg/24 hr. similar to that obtained after 60 hr. in Cerro de Pasco (altitude 14.200 ft) 5.648 mg/24 hs. (p>0.5). However, there was a considerable individual variation and no correlation between the TPR and the urinary excretion of testosterone. It is concluded that the determination of the TPR by 'urinary' methods is not adequate in circumstances of adrenal stimulation by ACTH. The excretion of radioactivity in the urine was similar at sea level and high altitude: 79.4 and 78.2% respectively; the same occurred with the 17-Ketosteroids for which mean values were 19.77 and 22.09 mg/48 hr. (p>0.5). (Author)

Descriptors :   (*TESTOSTERONE, METABOLISM), HIGH ALTITUDE, ADAPTATION(PHYSIOLOGY), URINE, EXCRETION, STEROIDS, PERU

Subject Categories : Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE