Accession Number : AD0673742

Title :   PHARMACOLOGICAL IMPROVEMENT OF CAPACITY OF PULMONARY CIRCULATION AT HIGH ALTITUDE.

Descriptive Note : Rept. no. 2 (Final) Apr 67-Apr 68,

Corporate Author : TOHO UNIV TOKYO (JAPAN) DEPT OF PHYSIOLOGY

Personal Author(s) : Asahina,Kazuo

Report Date : JUL 1968

Pagination or Media Count : 24

Abstract : The effect of ascorbic acid on increasing tolerance to hypoxia has been proved. The noticeable findings have been found in our experiments; (1) ascorbic acid moves from organs to blood in hypoxia and (2) the proportion of oxydized ascorbic acid is much larger in the heart than any other organs in hypoxia. The explanation for these findings have not yet been given. However, these results suggest that there may be some important relationship between ascorbic acid and heart activity which was proved in our previous experiments to be the most significant factor limiting the altitude tolerance. (Author)

Descriptors :   (*HYPOXIA, TOLERANCES(PHYSIOLOGY)), ASCORBIC ACID, BLOOD CIRCULATION, HEART, LUNG, DRUGS, ACCLIMATIZATION, HIGH ALTITUDE, JAPAN

Subject Categories : Anatomy and Physiology
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE