Accession Number : AD0674682

Title :   THE SYNTHESIS OF CANDIDATE ANTI-RADIATION COMPOUNDS.

Descriptive Note : Final progress rept. 1 Apr 66-31 Mar 67,

Corporate Author : EPOXYLITE CORP SOUTH EL MONTE CALIF

Personal Author(s) : Stoffey,Donald G.

Report Date : 07 MAR 1967

Pagination or Media Count : 12

Abstract : Several possible routes to cysteamine-thiophosphate disulfides were studied. Methods which contained acids other than the thiophosphoric acids or used water as the solvent gave no isolatable unsymmetrical disulfides. However, the symmetrical disulfides which would result from the disproportionation of the unsymmetrical disulfides were isolated in some cases. Three, O,O-dialkyl-S-2-acetaminoethylmercapto phosphorodithioates were prepared by the action of O,O-dialkyl phosphorodithioic acids on 2-acetaminoethyl 2-acetaminoethane thiolsulfonate. The corresponding alkylthioperoxide diphosphorothionate were also formed.

Descriptors :   (*RADIOPROTECTIVE AGENTS, SYNTHESIS(CHEMISTRY)), ORGANIC SULFUR COMPOUNDS, ORGANIC PHOSPHORUS COMPOUNDS, AMINES, PEROXIDES, SOLVENTS, ACIDS

Subject Categories : Pharmacology
      Organic Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE