Accession Number : AD0674682
Title : THE SYNTHESIS OF CANDIDATE ANTI-RADIATION COMPOUNDS.
Descriptive Note : Final progress rept. 1 Apr 66-31 Mar 67,
Corporate Author : EPOXYLITE CORP SOUTH EL MONTE CALIF
Personal Author(s) : Stoffey,Donald G.
Report Date : 07 MAR 1967
Pagination or Media Count : 12
Abstract : Several possible routes to cysteamine-thiophosphate disulfides were studied. Methods which contained acids other than the thiophosphoric acids or used water as the solvent gave no isolatable unsymmetrical disulfides. However, the symmetrical disulfides which would result from the disproportionation of the unsymmetrical disulfides were isolated in some cases. Three, O,O-dialkyl-S-2-acetaminoethylmercapto phosphorodithioates were prepared by the action of O,O-dialkyl phosphorodithioic acids on 2-acetaminoethyl 2-acetaminoethane thiolsulfonate. The corresponding alkylthioperoxide diphosphorothionate were also formed.
Descriptors : (*RADIOPROTECTIVE AGENTS, SYNTHESIS(CHEMISTRY)), ORGANIC SULFUR COMPOUNDS, ORGANIC PHOSPHORUS COMPOUNDS, AMINES, PEROXIDES, SOLVENTS, ACIDS
Subject Categories : Pharmacology
Distribution Statement : APPROVED FOR PUBLIC RELEASE