Accession Number : AD0675113

Title :   NEUTRALIZATION REACTION OF THE VENEZUELAN ENCEPHALOMYELITIS VIRUS BASED ON THE HEMAGGLUTINATION PHENOMENON,

Corporate Author : ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s) : Gaidamovich,S. Ya. ; Vagzhanova,V. A.

Report Date : DEC 1966

Pagination or Media Count : 8

Abstract : The neutralization reaction of the Venezuelan equine encephalomyelitis virus in tissue cultures, based on the phenomenon of hemagglutination, makes it possible to obtain results in 18 hours instead of the 72 hours required for an evaluation based on the cytopathological effect. When investigating the sera of convalescents in the neutralization reaction in tissue cultures, practically the same results are obtained during evaluation by both methods. The immune sera of rabbits gave significantly higher neutralization indices when evaluated according to hemagglutination. Complement-fixing antibodies in titers of 1:8--1:16 were still detected in the sera of convalescents 8 years following illness. (Author)

Descriptors :   (*VENEZUELAN EQUINE ENCEPHALOMYELITIS VIRUS, ANTIGEN ANTIBODY REACTIONS), NEUTRALIZATION, IMMUNE SERUMS, TISSUE CULTURE, SERODIAGNOSIS, USSR

Subject Categories : Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE