Accession Number : AD0675278

Title :   CHANGES IN THE RADIOSENSITIVITY OF ANIMALS AS A RESULT OF PREVIOUS X-RADIATION (IZMENENIE RADIOCHUVSTVITELNOSTI ZHIVOTNYKH V REZULTATE PREDVARITELNOGO RENTGENOVSKOGO OBLUCHENIYA),

Corporate Author : FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO

Personal Author(s) : Mezentsev,A. I. ; Gubin,G. D.

Report Date : 09 NOV 1967

Pagination or Media Count : 8

Abstract : In experiments on 245 albino rats, one group was subjected to a single total-body irradiation at a dose of 800 r and a second group was subjected to two irradiations at doses of 43 and then 800 r with a 7-day interval. A record was made of survival, weight change, changes in the Hb content and leukocyte count in the peripheral blood, the condition of the animals, and the histological index (DNA, RNA and glycogen content of the liver). Previous irradiation increased survival of irradiated animals 2-5-fold (with the exception of a group of animals with an initial weight higher than 300 g, where the survival rate remained unchanged). Radiation sickness of such pre-irradiated animals was less severe. In addition, the RNA and glycogen content of pre-irradiated animals changed only slightly. DNA content was decreased to the same extent in both groups of animals.

Descriptors :   (*RADIATION TOLERANCE, EXPERIMENTAL DATA), RADIATION SICKNESS, WHOLE BODY IRRADIATION, RESISTANCE(BIOLOGY), RADIATION DOSAGE, X RAYS, BODY WEIGHT, HEMATOLOGY, HISTOLOGY, NUCLEIC ACIDS, GLYCOGEN, RADIATION EFFECTS, RADIOBIOLOGY, RATS, USSR

Subject Categories : Radiobiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE