Accession Number : AD0676502

Title :   EFFECTS OF TWO ANTIHISTAMINE-CONTAINING COMPOUNDS UPON PERFORMANCE AT THREE ALTITUDES,

Corporate Author : CIVIL AEROMEDICAL INST OKLAHOMA CITY OKLA

Personal Author(s) : Higgins,E. Arnold ; Davis,Audie W. , Jr. ; Fiorica,Vincent ; Iampietro,P. F. ; Vaughan,John A.

Report Date : JUN 1968

Pagination or Media Count : 12

Abstract : In a study of 45 human subjects it was determined that a compound drug containing the antihistamine phenindamine did not statistically impair performance on a modified Mashburn coordinator. Another compound containing the antihistamine chlorpheniramine did impair performance. Performance was also impaired by increasing altitudes. The combined effects of the chlorpheniramine compound and increased altitude proved more detrimental to performance than the sum of the decrements that each influence caused when encountered separately. Although no significant performance decrement resulted from the administration of the phenindamine compound, undesirable side-effects were noted. (Author)

Descriptors :   (*FLIGHT CREWS, *ANTIHISTAMINICS), PERFORMANCE(ENGINEERING), OXYGEN, PH FACTOR, MOTOR REACTIONS, RESPIRATION, PERFORMANCE(HUMAN), DRUGS, BODY TEMPERATURE, AMINES

Subject Categories : Personnel Management and Labor Relations
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE