Accession Number : AD0676572

Title :   THE LOCALIZATION AND ACTIVITY OF ACETYLCHOLINESTERASE IN THE ORGAN OF CORTI IN ANIMALS EXPOSED TO POWERFUL MEDIUM-FREQUENCY SOUNDS (O LOKALIZATSII I AKTIVNOSTI ATSETILKHOLINESTERAZY V KORTIEVOM ORGANE ZHIVOTNYKH PRI VOZDEISTVII MOSHCHNYMI VYSOLOCHASTOTNYMI I SREDNECHASTOTNYMI ZVUKAMI),

Corporate Author : FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO

Personal Author(s) : Anichin,V. F.

Report Date : 17 JUL 1967

Pagination or Media Count : 15

Abstract : The localization of the activity of acetylcholinesterase strictly coincides with the internal and external spiral nervous plexus of the organ of Corti. A 6-hour exposure to powerful sound causes a sharp drop in acetylcholinesterase activity. In guinea pigs exposed to high-frequency sounds the sharpest drop in acetylcholinesterase activity is observed in the inferior helices, in guinea pigs exposed to medium-frequency sounds, in the superior and mediosuperior helices. In rats the sharpest drop in enzyme activity is observed in the superior and regions of the medial helices under exposure to both high-frequency and medium-frequency sounds, which can evidently be explained by the range of perceptible sounds. The drop in acetylcholinesterase activity after exposure to interrupted sounds carries the same character as that after exposure to stable sounds of the same frequency and intensity. (Author)

Descriptors :   (*ACETYLCHOLINESTERASE, *STRESS(PHYSIOLOGY)), EAR, NERVOUS SYSTEM, HIGH FREQUENCY, SOUND, TISSUES(BIOLOGY), EXPOSURE(PHYSIOLOGY), VISUAL INSPECTION, NERVE FIBERS, USSR

Subject Categories : Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE