Accession Number : AD0676685

Title :   THE ROLE OF CATECHOLAMINES AND SEROTONIN IN THE PROCESS OF ADAPTATION TO HIGH ALTITUDE.

Descriptive Note : Final rept.,

Corporate Author : UNIVERSIDAD NACIONAL DE TRUJILLO (PERU) DEPARTAMENTO DE FISIOLOGIA

Personal Author(s) : Medina,Arnoldo ; Utano,Luis ; Olava,Gilberto

Report Date : SEP 1968

Pagination or Media Count : 11

Abstract : This work is relationed with the study of the catecholamines and serotonin in the process of adaptation to high altitude. The effects of hypoxia (12.85% O2 in N2) on the pulmonary artery pressure of dogs have been studied, as well as the variations in the levels of Serotonin and Catecholamines in the blood of the same artery. Hypoxia produced pulmonary hypertension in the dogs studied, and at the same time an increase in the level of Serotonin in the blood of the pulmonary artery was produced. The dogs reserpinized had hypertension pulmonary. This result is expounded in relation to a reflex vasoconstriction, which is mediated by Serotonin. (Author)

Descriptors :   (*AMINES, *ADAPTATION(PHYSIOLOGY)), SEROTONIN, HYPOXIA, BLOOD PRESSURE, HYPERTENSION, ARTERIES, RESERPINE, CONTRACTION, REFLEXES, RESPONSE(BIOLOGY), HIGH ALTITUDE

Subject Categories : Biochemistry
      Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE