Accession Number : AD0680224

Title :   DEVELOPMENT OF AN ORALLY EFFECTIVE INSECT REPELLENT.

Descriptive Note : Annual progress rept., 1 Nov 67-31 Oct 68,

Corporate Author : IIT RESEARCH INST CHICAGO IL

Personal Author(s) : Kashin, Philip

Report Date : NOV 1968

Pagination or Media Count : 54

Abstract : The objective of this program is to develop mosquito repellents for topical or systemic use that will be more potent, longer lasting, and afford more uniform protection than those currently available. The testing of compounds of mosquito repellency was continued. Repellency data was derived from an electronic 'bitometer-timer' apparatus (which yields the percentage of total time of actual biting), and from the percentage of mosquitoes that engorged blood during the test period. The sum of these two parameters, the repellency index, was analyzed for statistical significance for differences from controls in a specialized digital computer program. Substances that resemble the structure of the neuroinhibitor, gamma-aminobutyric acid (GABA), in terms of their electronic distribution, are generally significantly repellent at low levels of application. (Author)

Descriptors :   (*INSECT REPELLENTS, EFFECTIVENESS), CULICIDAE, FATTY ACIDS, CARBON DIOXIDE, NERVE IMPULSES, INHIBITION, EXCITATION, STIMULATION(PHYSIOLOGY), BLATTIDAE, CENTRAL NERVOUS SYSTEM, TABLES(DATA), BIOASSAY.

Subject Categories : Biochemistry
      Hygiene and Sanitation

Distribution Statement : APPROVED FOR PUBLIC RELEASE