Accession Number : AD0680403
Title : MEASURING IRON METABOLISM IN HEMATOPOIETIC CENTERS USING 59Fe IN THE PRESENCE OF 51Cr AND 125I.
Descriptive Note : Rept. for Jan-Mar 68,
Corporate Author : SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX
Personal Author(s) : Strong,Guy M. ; Logsdon,Donald F. ; Green,James F.
Report Date : SEP 1968
Pagination or Media Count : 12
Abstract : The 59Fe concentration in the hematopoietic centers (sacrum, liver, and spleen) can be accurately and reproducibly determined with a rate meter, a photomultiplier probe, and a scintillation crystal detection system. When the three isotopes 51Cr, 125I, and 59Fe are present, a 10 mm. lead filter screens out essentially all of the chromium and iodine isotope activity while allowing 60% of the 59Fe activity to pass. The use of a constant standard and the calculation of the R factor (area of radiation site/area of standard) makes decay correction unnecessary. Since iron metabolism is normally measured as part of a larger study of erythrokinetics and blood parameters, this technic allows two or more isotope studies of hematopoietic centers to be conducted simultaneously. (Author)
Descriptors : (*IRON, *METABOLISM), (*RADIOBIOLOGY, METABOLISM), LIVER, SPLEEN, HEMOGLOBIN, RADIOACTIVE ISOTOPES, CHROMIUM, IODINE, SCINTILLATION COUNTERS
Subject Categories : Anatomy and Physiology
Distribution Statement : APPROVED FOR PUBLIC RELEASE