Accession Number : AD0680948

Title :   EXPERIMENTAL STUDY OF ACUTE AND CHRONIC INJURY TO RENAL TUBULES.

Descriptive Note : Rept. no. 5 (Final), 1 Dec 62-30 Jun 68,

Corporate Author : JOHNS HOPKINS UNIV BALTIMORE MD SCHOOL OF MEDICINE

Personal Author(s) : Heptinstall,Robert H. ; Mostofi,F. K.

Report Date : NOV 1968

Pagination or Media Count : 43

Abstract : The work carried out was multifaceted, dealing with the many factors concerned in acute and chronic injury to renal tubules. In view of the fact that most tubular lesions are the consequence of vascular impairment, many of the studies involved an examination of the behavior of arteries, arterioles and glomeruli in the face of different stimuli. The juxtaglomerular apparatus is intimately concerned in the regulation of blood flow and experiments were carried out to shed light on this structure. The factors concerned in the stimulus for hyperplasia of the juxtaglomerular apparatus were studied to test the validity of the notion that the tonicity of the filtrate acting on the macula densa is of importance. (Author)

Descriptors :   (*KIDNEYS, WOUNDS AND INJURIES), NECROSIS, HYPERTENSION, DISEASES, ARTERIES, CELLS(BIOLOGY), HEMATOLOGY, ELECTRON MICROSCOPY, HEMOGLOBIN, PHOSPHORIC MONOESTER HYDROLASES, ESCHERICHIA COLI, THYROID GLAND, ACIDOSIS, RETICULOENDOTHELIAL SYSTEM, STIMULATION(PHYSIOLOGY), BLOOD CIRCULATION

Subject Categories : Anatomy and Physiology
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE