Accession Number : AD0681230

Title :   THE TOXICITY OF DIMETHYL SULFOXIDE AT FOUR CONCENTRATIONS.

Descriptive Note : Technical rept. Sep 65-Apr 66,

Corporate Author : EDGEWOOD ARSENAL MD

Personal Author(s) : Worthley,E. G. ; Schott,C. D.

Report Date : DEC 1968

Pagination or Media Count : 16

Abstract : The toxicity of dimethyl sulfoxide in mice was measured by giving intraperitoneal doses in concentrations of 25, 50, 75, and 100 percent. It was found that the LD50 increases somewhat as the concentration decreases, but the increase is only significant at the interval between 50 and 25 percent; time to death increased at low concentrations compared to high concentrations. The LD50 values found for the above four concentrations were 15.4, 12.8, 11.9, and 10.9 gm/kg, respectively. (Author)

Descriptors :   (*SULFOXIDES, *TOXICITY), CONCENTRATION(CHEMISTRY), LETHAL DOSAGE, MICE

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE