Accession Number : AD0681894

Title :   STUDIES ON STORED LIQUID WHOLE BLOOD. II. USE OF PACKED RED CELLS.

Descriptive Note : Interim rept. Jan 67-Jan 68,

Corporate Author : ARMY MEDICAL RESEARCH LAB FORT KNOX KY

Personal Author(s) : Shields,Charles E.

Report Date : 01 OCT 1968

Pagination or Media Count : 12

Abstract : Liquid whole blood collected in ACD or ACD with adenine was studied as units stored with or without plasma over 14 to 28 days. Comparisons were made using various tests, with in vivo posttransfusion survival being the primary guideline. The adverse effects resulting from storage appeared more slowly in units with plasma compared to units without plasma. The inclusion of adenine to either packed or non-packed units was associated with even less evidence of storage damage. Using the criteria of over 70% survival as signifying adequate preservation, the average survival value for each group was better when the plasma was present, and even higher when adenine had been added. All tested groups had average values over 70% after 21 days of storage. Blood stored for 28 days with adenine had over 70% with or without plasma. Though the storage damage became more apparent in units without plasma, the average survival value would suggest that the packed units were still useful after 21 days of storage, with extension to 28 days when ACD with adenine was used. (Author)

Descriptors :   (*BLOOD, STORAGE), ERYTHROCYTES, BLOOD TRANSFUSION, PRESERVATION, ADENINE, BLOOD PLASMA, IN VIVO ANALYSIS, BLOOD CHEMISTRY, TABLES(DATA)

Subject Categories : Anatomy and Physiology
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE