Accession Number : AD0682592

Title :   CERTAIN TOXIGENIC PROPERTIES OF CLOSTRIDIUM PERFRINGENS, TYPES D AND E,

Corporate Author : ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s) : Marasanova,L. P.

Report Date : JAN 1969

Pagination or Media Count : 3

Abstract : Protoxin was isolated in vivo by Bychenko's method (by treating the centrifugate of an 18 hour culture of Cl. perfringens with a 0.5% physiological solution of crystalline trypsin). The toxic properties were determined during and after treatment. The titer taken for the toxin was the smallest lethal dose for mice introduced internally within a 48 hour period. An index of activation was determined by comparing the titers of activated and inactivated toxins. (Author)

Descriptors :   (*CLOSTRIDIUM PERFRINGENS, TOXINS AND ANTITOXINS), IN VIVO ANALYSIS, IN VITRO ANALYSIS, DOSAGE, TRYPSIN, EMBRYONATED EGG TECHNIQUE, MICE, USSR

Subject Categories : Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE