Accession Number : AD0683530

Title :   CEREBRAL BLOOD FLOW DURING HYPERTHERMIA.

Descriptive Note : Annual progress rept., 1 Feb-30 Nov 68,

Corporate Author : RUTGERS - THE STATE UNIV NEW BRUNSWICK N J DEPT OF PHYSIOLOGY

Personal Author(s) : Frankel,Harry M.

Report Date : DEC 1968

Pagination or Media Count : 28

Abstract : The method of Reinmuth et al for determining cerebral blood flow (CBF) (Arch. Neurol., 12:49-66, 1965) has been adapted for use on dogs. Measurements of CBF, cerebral vascular resistance (CVR) and cerebral oxygen and glucose consumptions were made at rectal temperatures (Tr) of 37.5, 40, 42 and 43C. Responses at 43C were decreased compared to the values obtained at 42C. The data suggested that at Tr 42C the maximum capacity of circulation to supply O2, under natural conditions, may have been reached. Work is continuing on the problem: (a) to determine whether maximal delivery occurred at 42C (b) to determine the parameters of control with elevated Tr. (Author)

Descriptors :   (*FEVERS, BLOOD CIRCULATION), (*BLOOD CIRCULATION, BRAIN), MEASUREMENT, DOGS, RESPONSE(BIOLOGY), BODY TEMPERATURE, OXYGEN CONSUMPTION, GLUCOSE, LABELED SUBSTANCES, TABLES(DATA), BLOOD PRESSURE

Subject Categories : Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE