Accession Number : AD0683563

Title :   MIBT AND BACTERIOPHAGE MULTIPLICATION.

Descriptive Note : Research Communication no. 85,

Corporate Author : DOUGLAS AIRCRAFT CO INC HUNTINGTON BEACH CALIF ADVANCED RESEARCH LABS

Personal Author(s) : Norman,David ; De La Cruz,Margaret

Report Date : DEC 1968

Pagination or Media Count : 24

Abstract : N-methyl isatin-beta-thiosemicarbazone, a known inhibitor of pox-virus in vitro and in vivo, is without effect upon the virulent bacteriophage T4, T4B, T4Bo1, or the temperate phage lambda grown in E. coli. At concentrations which show striking anti-viral activity against the pox-virus in tissue culture, this compound exhibits no activity in the processes of adsorption, penetration, or replication of the bacteriophage studied. (Author)

Descriptors :   (*INDOLES, *ANTIMETABOLITES), (*BACTERIOPHAGES, INDOLES), POX VIRUSES, ESCHERICHIA COLI, DEOXYRIBONUCLEIC ACIDS, IN VITRO ANALYSIS

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE