Accession Number : AD0684781

Title :   A STUDY OF BLOOD pH, SERUM POTASSIUM CONCENTRATION, AND STRESS IN THE SQUIRREL MONKEY (SAIMIRI SCIUREUS),

Corporate Author : NAVAL AEROSPACE MEDICAL INST PENSACOLA FLA

Personal Author(s) : Wheeler,Thomas E. ; New,Albert E.

Report Date : 01 DEC 1968

Pagination or Media Count : 13

Abstract : Serum potassium concentration in the squirrel monkey is elevated as compared to that of other commonly used laboratory animals. This study was designed to determine if the levels observed for the potassium ion are related to a change in pH. Related parameters of serum CO2 and pCO2 are reported. Data accumulated from the study of biochemical parameters in the squirrel monkey cannot be rationalized in terms of in vivo buffer systems. Serum potassium and CO2 appear to be related to altered pH, since low pH values were found in conjunction with low CO2 and high potassium. Stress brought about by restraint during blood collection was found to significantly alter the pH and potassium when these values were compared with those from tranquilized and anesthetized squirrel monkeys which were used as controls. The squirrel monkey appears to present an extreme stress response and thus may be a highly desirable biological system in which to elucidate those in vivo changes associated with stress. (Author)

Descriptors :   (*STRESS(PHYSIOLOGY), *BLOOD CHEMISTRY), PH FACTOR, POTASSIUM, CONCENTRATION(CHEMISTRY), BLOOD SERUM, CARBON DIOXIDE, RESPONSE(BIOLOGY), MONKEYS, IN VIVO ANALYSIS

Subject Categories : Biochemistry
      Anatomy and Physiology
      Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE