Accession Number : AD0685171

Title :   DESIGN AND EVALUATION OF EXPERIMENTS WITH LABYRINTHINE STATORECEPTORS.

Descriptive Note : Technical rept.,

Corporate Author : PITTSBURGH UNIV PA DEPT OF PHARMACOLOGY

Personal Author(s) : Werner,Gerhard ; Sacks,Hershel ; Fierst,James

Report Date : 15 MAR 1969

Pagination or Media Count : 18

Abstract : The report establishes a theoretical framework and computational procedures which lead to an experimental strategy for distinguishing between two alternative modes of operation of the vestibular statoreceptors: the question is whether individual kinocilia in the maculae sacculi and utriculi are innervated by single vestibular afferent fibers; or else, whether convergence of neural discharges originating from several kinocilia with different orientation of functional polarization occurs in vestibular afferent fibers. If the former condition prevails, it is possible to calculate the vector of maximal sensitivity of each kinocilium from the polar plot of nerve discharge rates, obtained at suitable head positions in the gravity field. The principle of the procedure consists in the matching of experimental data with a computer simulated model of sacculus and utriculus. (Author)

Descriptors :   (*MEDICAL EQUIPMENT, EAR), (*VESTIBULAR APPARATUS, TEST METHODS), NERVE FIBERS, NERVE IMPULSES, SENSITIVITY, MATHEMATICAL MODELS, SIMULATION, VECTOR ANALYSIS, TRANSFORMATIONS(MATHEMATICS)

Subject Categories : Medical Facilities, Equipment and Supplies

Distribution Statement : APPROVED FOR PUBLIC RELEASE