Accession Number : AD0686793

Title :   QUANTIFIED LSD EFFECTS ON EGO STRENGTH,

Corporate Author : MINNESOTA UNIV MINNEAPOLIS DEPT OF PHARMACOLOGY

Personal Author(s) : Marrazzi,Amedeo S. ; Meisch,Richard A. ; Pew,William L. ; Bieter,Thomas G.

Report Date : 1966

Pagination or Media Count : 24

Abstract : It was found, in support of the postulated nature of hallucination as an inadequate integration of new with stored information resulting in aberrant perception, that subclinical doses of LSD bring out a latent or accentuate an existing difficulty in resolving the perceptual conflict experimentally induced in psychotics as distinguished from in neurotics and normals, but add little if this conflict is so great that active hallucination already exists at the time of LSD administration. It is felt that this kind of drug evaluation of cerebral integration can help identify and measure abnormality characteristic of the forms of mental disturbance in which a dissociative process is a fundamental feature. Contingent on further substantiation, the proposed LSD index holds promise of supplying the 'clinical yardstick' to help in diagnosis and in following the course of mental illness and the efficacy of therapy. (Author)

Descriptors :   (*LYSERGIC ACIDS, *MENTAL DISORDERS), HALLUCINOGENS, NEUROSES, PSYCHOSES, MEASUREMENT, DIAGNOSIS(MEDICINE), THERAPY, PERCEPTION

Subject Categories : Medicine and Medical Research
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE