Accession Number : AD0686923

Title :   DIE TOXIKOLOGISCHE UND HYGIENISCHE BEDEUTUNG DES OZONS (The Toxicological and Hygienic Significance of Ozone),

Corporate Author : EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZURICH (SWITZERLAND)

Personal Author(s) : Gilgen,Von A. ; Wanner,H. U.

Report Date : 1966

Pagination or Media Count : 18

Abstract : The acute toxicity of ozone to laboratory animals is reported as being diverse and varies from species to species. Chronical exposure results in damage to the respiratory organs, i.e. in bronchitis and lung emphysema, limitation in weight increase of young animals and reduced urine acidity. When exposing man to 4 to 5 ppm, a lung oedema develops within a few hours. Lower concentrations primarily affect respiration by irritation and cause headaches and nausea. In animals, the exposure to low ozone concentrations produces immunity to subsequently applied lethal doses; this phenomenon is designated as tolerance. The mode in which ozone become biologically effective, is not yet fully clarified. Presumably free radicals causing oxidation processes are formed, similar to those in the case of radiation from radioactive substance. These processes in turn set free adrenaline, noradrenaline and bradykinin. The strongest bacteriostatic and bacteriocidal effects of ozone are obtained at high relative humidity and low temperature. In practice the germicidal effect of ozone can only be applied in preparing and sterilizing water. The deodoring effect of ozone is generally accepted. This, however, requires concentrations exceeding the tolerable limitations. (Author)

Descriptors :   (*OZONE, TOXICITY), (*HYGIENE, OZONE), EXPOSURE(PHYSIOLOGY), RESPIRATORY SYSTEM, PATHOLOGY, CONCENTRATION(CHEMISTRY), DOSAGE, BODY WEIGHT, LABORATORY ANIMALS, HUMANS, RESPIRATION, IMMUNITY, STERILIZATION, WATER, SANITARY ENGINEERING, SWITZERLAND

Subject Categories : Hygiene and Sanitation
      Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE