Accession Number : AD0688053

Title :   THE FORMATION OF ANTIBIOTIC-RESISTANT STRAINS OF S. TYPHI AND SH. DYSENTERIAE FLEXNERI UNDER CONDITIONS OF CONTINUOUS CULTURING,

Corporate Author : ARMY FOREIGN SCIENCE AND TECHNOLOGY CENTER WASHINGTON D C

Personal Author(s) : Kovalevskaya,A. N.

Report Date : 09 APR 1969

Pagination or Media Count : 9

Abstract : Five strains of typhoid bacilli and five strains of dysentry flexneri bacilli were grown in continuous culture with increment doses of mycerin and streptomycin. Data are presented on antibiotic concentrations required for the lowest and highest resistance of each strain under various conditions. Antibiotic resistance developed more rapidly in continuous culture than in the control stationary cultures, and variants were observed with modified antigentics and enzymic properties. (Author)

Descriptors :   (*SHIGELLA FLEXNERI, RESISTANCE(BIOLOGY)), (*SALMONELLA TYPHOSA, RESISTANCE(BIOLOGY)), ANTIBIOTICS, CULTURE MEDIA, GROWTH(PHYSIOLOGY), CONCENTRATION(CHEMISTRY), MUTATIONS, GENETICS, ENZYMES, IDENTIFICATION, USSR

Subject Categories : Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE