Accession Number : AD0688864

Title :   AN AUTOMATED METHOD FOR CHOLINESTERASE MEASUREMENTS IN THE RHESUS MONKEY.

Descriptive Note : Technical rept.,

Corporate Author : EDGEWOOD ARSENAL MD

Personal Author(s) : Ward,F. Prescott

Report Date : MAY 1969

Pagination or Media Count : 17

Abstract : This report describes optimum conditions for the automated thiocholine measurement of cholinesterase in samples of whole blood, plasma, and RBC's from rhesus monkeys. The technique is rapid, sensitive, highly reproducible, directly measures a product of ChE action, and requires a small sample for assay. The effects of substrate concentration of ChE activity, and the effects of hemolysis on RBC ChE activity have been studied. A technique for the microdetermination of RBC ChE has also been developed. (Author)

Descriptors :   (*CHOLINESTERASE, MEASUREMENT), AUTOMATION, HEMOLYSIS, MONKEYS, BLOOD CHEMISTRY, MICROANALYSIS

Subject Categories : Biochemistry
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE