Accession Number : AD0689642

Title :   EFFECTS OF LOCAL ALTERATIONS OF pCO2 AND pH ON CEREBROVASCULAR RESISTANCE IN ISOLATED DOG HEADS,

Corporate Author : ALBERTA UNIV EDMONTON

Personal Author(s) : Emerson,Thomas E. , Jr. ; Heath,Charles

Report Date : 1969

Pagination or Media Count : 5

Abstract : The local effects of graded increases and decreases of paCO2 and pH on cerebral vascular resistance were determined in isolated dog heads. Two preparations were utilized: In the first series, a donor dog was included in the extracorporeal circulation to supply blood to the constant flow perfused, decapitate head; in the second series, the donor dog was replaced with an oxygenator-reservoir system. Results indicate that the direct effect of increasing paCO2 and decreasing pH is a fall of cerebral vascular resistance and vice versa. (Author)

Descriptors :   (*CEREBROVASCULAR SYSTEM, RESISTANCE(BIOLOGY)), BRAIN, BLOOD CIRCULATION, CARBON DIOXIDE, PH FACTOR, BLOOD VESSELS, CANADA

Subject Categories : Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE