Accession Number : AD0690210

Title :   EVALUATION OF SYNTHETIC FILMS AS WOUND COVERS.

Descriptive Note : Final comprehensive rept.,

Corporate Author : JOHNS HOPKINS UNIV BALTIMORE MD SCHOOL OF MEDICINE

Personal Author(s) : Walder,Arnold I.

Report Date : 07 JUL 1969

Pagination or Media Count : 9

Abstract : A polyamino acid film was developed which functions as a satisfactory, temporary biological dressing in the rat model described in this study. This polyamino acid is a synthetic copolymer of two amino acids, appears as a water-white polypeptide film, has a tensile strength of 4,5000 p.s.i., is heat stable to 290 degrees C., and remains flexible at dry-ice temperatures. Therefore, in addition to its biological properties it is also easily sterilized, has a long shelf life and can be synthesized in quantities great enough to meet the demands of a human homograft substitute. The polymer film, polymer film plus a gauze laminate and the polymer film plus a velour laminate were compared and evaluated as wound covers. The evaluation was based on gross appearance of the wound, adherence of wound covers, accumulation of pus beneath the wound covers, mortality and histological and bacteriological examination. (Author)

Descriptors :   (*AMINO ACIDS, *DRESSINGS), WOUNDS AND INJURIES, STERILIZATION, POLYMERS, HEALING, BIOLOGICAL CONTAMINATION, PEPTIDES, FILMS

Subject Categories : Medical Facilities, Equipment and Supplies

Distribution Statement : APPROVED FOR PUBLIC RELEASE